A Doctor, a Mutation and a Potential Cure for AIDS

A Bone Marrow Transplant to Treat a Leukemia Patient Also Gives Him Virus-Resistant Cells; Many Thanks, Sample 61

The startling case of an AIDS patient who underwent a bone marrow transplant to treat leukemia is stirring new hope that gene-therapy strategies on the far edges of AIDS research might someday cure the disease.

The patient, a 42-year-old American living in Berlin, is still recovering from his leukemia therapy, but he appears to have won his battle with AIDS. Doctors have not been able to detect the virus in his blood for more than 600 days, despite his having ceased all conventional AIDS medication. Normally when a patient stops taking AIDS drugs, the virus stampedes through the body within weeks, or days.

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Tissue Genesis Applies CE Mark to Its Adult Stem Cell Isolation System

Conformity Marking Allows Device to be Marketed Throughout Europe

HONOLULU, Nov 18, 2008 (BUSINESS WIRE) -- Tissue Genesis, Inc., an innovator of advanced tissue engineering and cell therapy solutions, today announced that effective immediately, the Tissue Genesis Cell Isolation System will be available to the European marketplace.

The Tissue Genesis Cell Isolation System is a fully automated system that recovers potentially regenerative cells from a patient's own fat in about an hour, with minimal operator intervention. No tissue pre-processing is required. The system accepts adipose

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Doctors transplant windpipe with stem cells

LONDON – Doctors have given a woman a new windpipe with tissue grown from her own stem cells, eliminating the need for anti-rejection drugs. "This technique has great promise," said Dr. Eric Genden, who did a similar transplant in 2005 at Mount Sinai Hospital in New York. That operation used both donor and recipient tissue. Only a handful of windpipe, or trachea, transplants have ever been done.

If successful, the procedure could become a new standard of treatment, said Genden, who was not involved in the research.

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IFATS Series: FGF-2-induced HGF Secretion By Adipose-Derived Stromal Cells Inhibits Post-Injury Fibrogenesis Through A JNK-Dependent Mechanism — Suga et al., 10.1634/stemcells.2008-0261 — Stem Cells

Dr Kotaro Yoshimura at the Department of Plastic Surgery, Tokyo University Japan has created new breast tissue from stem cells. It’s hoped this could provide an important development for women who have had their breasts removed due to breast cancer. Cynics believe it will just fuel a new craze for a healthier alternative to silicon for a more natural small breasts enhancement.

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World's first full-service medical research & development centre opens in Jordan

Dubai, October 29 2008: A world-first is bagged by the Jordanian capital, Amman with the opening of the Philadelphia Biological and Medical Product Development Centre (on October 30). 

The Centre is said to be the only healthcare product development hub worldwide that provides preclinical evaluation, full-service clinical research, core lab facilities, as well as cell engineering and culturing. 

According to Peggy Farley, the Centre's Chairperson, it is geared to place the Middle East region firmly on the map as a global medical technology leader. Farley is also co-founder of the Ascent Medical Technology Funds, including Fund II which is the financial instrument providing the funding for the project. 

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Fat cells might aid heart attack therapy

The University of Houston researchers led by Associate Professor Stanley Kleis say adipose-derived stromal cells, or ADSCs, are found in fatty tissue.

When a person has a heart attack, the heart's cells do not get enough oxygen-rich blood, and some of them die, leaving behind damaged tissue. The researchers said ADSCs are similar to stem cells in that they can potentially develop into different types of cells, as well as producing chemicals that might protect or rejuvenate heart muscle.

"If we can show this conclusively, then we can develop a procedure that doctors can use to inject the cells into a heart attack patient's heart and can either protect or even help regrow the heart muscles," Kleis said.

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