Bioheart Receives Notice of Allowance for Nine New U.S. Patent Claims for Utilizing Electrical Stimulation to Enhance Stem Cell Regeneration of Damaged Heart Muscle

SUNRISE, Fla., Nov. 6, 2008 (GLOBE NEWSWIRE) -- Bioheart, Inc. (Nasdaq:BHRT) announced today that it has received a Notice of Allowance from the United States Patent and Trademark Office for nine new patent claims covering the use of electrical stimulation to enhance stem cell regeneration of damaged heart muscle.

The invention and its claims are deemed to be pioneering in that they harness the natural electro-chemical instructional program that teaches stem cells to become heart muscle and then apply this process to damaged heart muscle in patients suffering of heart failure. The stimulation not only attracts stem cells with a homing signal but also causes the release of beneficial proteins. The stimulation method may be applied with or without the injection of stem cells. The claims of the patent also cover pre-conditioning stem cells towards a cardiac phenotype by electrically stimulating them during culture before implantation into damaged heart muscle.

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